Looking for a reliable Cranberry Extract Proanthocyanidins manufacturer? Botanical Essence specializes in high-quality, standardized cranberry PACs extract with guaranteed potency, purity, and consistency. Our proanthocyanidin-rich cranberry extract is meticulously processed to deliver superior efficacy in urinary tract health, antioxidant support, and anti-adhesion applications.
For inquiries, contact us at [email protected].
What Is Cranberry Extract Proanthocyanidins (PACs)?
Cranberry Extract Proanthocyanidins (PACs) are a class of bioactive polyphenols uniquely abundant in Vaccinium macrocarpon (American cranberry). Unlike the B-type PACs found in grapes and other fruits, cranberry PACs are A-type proanthocyanidins, which exhibit a distinctive molecular structure that enhances their anti-adhesion properties against uropathogenic bacteria, particularly E. coli.
Key Scientific Insights on Cranberry PACs
- Mechanism of Action: A-type PACs inhibit bacterial adhesion to the urinary tract epithelium, preventing colonization and reducing the risk of urinary tract infections (UTIs).
- Clinical Efficacy: Research, including multicenter randomized controlled trials (RCTs), demonstrates that daily intake of ≥36 mg PACs significantly lowers UTI recurrence in women.
- Standardization Matters: To ensure efficacy, cranberry extract must be standardized to a minimum 50% PACs content—our product meets and exceeds this benchmark.
Beyond urinary health, cranberry proanthocyanidins also exhibit:
✔ Antioxidant & anti-inflammatory effects (supporting gut and cardiovascular health)
✔ Potential anti-cancer properties (modulating cell proliferation and apoptosis)
✔ Prebiotic-like activity (promoting beneficial gut microbiota)
Product Specification: High-Purity Cranberry PACs Extract
Our Cranberry Extract Proanthocyanidins is manufactured under strict GMP, ISO, HACCP, and FDA-registered facilities, ensuring pharmaceutical-grade purity and consistency.
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | Violet fine powder | Visual inspection |
| Odor & Taste | Characteristic cranberry | Organoleptic |
| Assay (PACs) | ≥50% | UV (EP Standard) |
| Particle Size | 100% pass 80 mesh | 80 Mesh Screen |
| Identification | Positive | TLC |
| Loss on Drying | ≤5.0% | CP2015 |
| Heavy Metals | NMT 10 ppm | Atomic Absorption |
| Lead (Pb) | NMT 3 ppm | Atomic Absorption |
| Arsenic (As) | NMT 2 ppm | Atomic Absorption |
| Mercury (Hg) | NMT 0.1 ppm | Atomic Absorption |
| Total Plate Count | NMT 3,000 cfu/g | CP2015 |
Additional Quality Assurance
✅ PAH EP Standard Compliant – Free from polycyclic aromatic hydrocarbons
✅ Pesticide Residue Free – Meets EP/USP/CP pesticide standards
✅ DNA-Verified Authenticity – Confirmed as 100% Vaccinium macrocarpon
✅ Full COA & Third-Party Testing – Available upon request
Key Benefits & Applications of Cranberry PACs Extract
1. Urinary Tract Health
- Prevents bacterial adhesion (E. coli, Proteus mirabilis)
- Reduces UTI recurrence (clinically validated at 36 mg/day)
- Supports bladder and kidney function
2. Gut & Digestive Wellness
- Modulates gut microbiota (reduces harmful bacteria, supports beneficial strains)
- Anti-inflammatory effects (may alleviate IBD symptoms)
- Potential colon cancer prevention (inhibits tumorigenesis in DSS-AOM models)
3. Antioxidant & Cardiovascular Support
- Neutralizes free radicals (higher ORAC value than vitamin C)
- Improves endothelial function (supports heart health)
- Reduces oxidative stress (linked to chronic disease prevention)
4. Anti-Cancer & Cell Protective Effects
- Inhibits cancer cell proliferation (studies on breast, prostate, colon cancers)
- Induces apoptosis (programmed cell death in malignant cells)
- Modulates signaling pathways (NF-κB, MAPK, PI3K/Akt)
5. Formulation & Industry Applications
✔ Dietary Supplements (capsules, tablets, softgels, gummies)
✔ Functional Foods & Beverages (juices, teas, energy bars)
✔ Nutraceuticals & Herbal Remedies (UTI prevention blends)
✔ Cosmeceuticals (antioxidant-rich skincare formulations)
✔ Pharmaceutical Excipients (adjunct therapy for UTIs)
Compatibility Note: Soluble in water, ethanol, and propylene glycol; stable under normal storage conditions (cool, dry, sealed).
Why Choose Botanical Essence for Cranberry PACs Extract?
✅ Superior Quality & Consistency
- Standardized to ≥50% PACs (ensuring optimal bioactivity)
- Batch-to-batch uniformity (strict QC from raw material to final product)
- Traceable sourcing (premium North American cranberries)
✅ Regulatory & Safety Compliance
- ISO 22000, KOSHER, HALAL, SC Certified
- FDA Registered Facility
- Non-GMO, Gluten-Free, Allergen-Free
✅ Supply Chain & Logistics Advantages
- Ready stock available (fast lead times for bulk orders)
- Flexible packaging (25 kg/drum, customizable options)
- Global shipping expertise (DHL, FedEx, sea freight)
✅ Technical & Customization Support
- Full-spectrum testing reports (COA, MSDS, microbiological analysis)
- Custom formulations (adjustable PACs concentration, blends with other extracts)
- R&D collaboration (assistance in product development)
Packaging, Storage & Shelf Life
| Parameter | Details |
|---|---|
| Packaging | 25 kg/fiber drum (double plastic bag inside) |
| Storage | Store in a cool, dry place, away from direct sunlight |
| Shelf Life | 2 years (when stored properly in sealed packaging) |
| Custom Options | Private labeling, bulk packaging, and OEM services available |
Your Trusted Partner in Botanical Extracts
At Botanical Essence, we combine cutting-edge extraction technology with rigorous quality control to deliver premium cranberry PACs extract that meets the highest industry standards. Whether you're a nutraceutical manufacturer, food & beverage producer, or pharmaceutical developer, our high-purity, bioavailable cranberry proanthocyanidins provide a reliable, science-backed solution for your formulations.
Contact us today at [email protected] to discuss bulk pricing, samples, or custom requirements.
