Product Overview
Dihydromyricetin Extract (DHM) is a highly bioavailable flavonoid compound derived from the Hovenia dulcis plant, a traditional botanical revered in East Asian medicine for its liver-protective and detoxifying properties. As a standardized plant extract, dihydromyricetin powder delivers a concentrated dose of active compounds, offering significant potential in alcohol metabolism support, liver health enhancement, and neuroprotective applications.
At Botanical Essence, we specialize in the extraction, purification, and supply of high-purity dihydromyricetin extract, ensuring consistent potency, superior bioavailability, and strict compliance with international quality standards. Our 98% dihydromyricetin extract is meticulously processed to retain its natural efficacy, making it an ideal ingredient for nutraceuticals, functional beverages, dietary supplements, and pharmaceutical formulations.
Botanical Source & Extraction Process
Natural Origin
Dihydromyricetin is primarily sourced from the dried fruit and seeds of Hovenia dulcis (Japanese Raisin Tree), a deciduous plant native to East Asia. This botanical has been traditionally used to alleviate alcohol intoxication, support liver function, and promote detoxification.
Advanced Extraction & Purification
Our dihydromyricetin extract is produced using state-of-the-art extraction techniques, including:
- Solvent-free or ethanol-based extraction to ensure high purity and minimal residual solvents.
- Chromatographic purification to isolate and concentrate the active compound.
- Spray drying or freeze-drying to produce a fine, free-flowing powder with optimal stability.
The result is a highly standardized extract with ≥98% dihydromyricetin content, verified through HPLC (High-Performance Liquid Chromatography) analysis.
Key Specifications & Quality Standards
Our dihydromyricetin extract powder undergoes rigorous quality control testing to meet pharmaceutical and food-grade standards. Below are the certified specifications from our latest Certificate of Analysis (COA):
| Parameter | Specification | Test Result | Method |
|---|---|---|---|
| Dihydromyricetin Content | ≥98.00% | 98.07% | HPLC |
| Appearance | Fine Powder | Conforms | Visual Inspection |
| Color | Light Yellow to Off-White | Off-White | Visual Inspection |
| Odor | Characteristic | Conforms | Organoleptic |
| Taste | Characteristic | Conforms | Organoleptic |
| Loss on Drying | ≤2.0% | 1.68% | 2h at 105°C |
| Ash Content | ≤1.0% | 0.44% | 5h at 600°C |
| Heavy Metals | |||
| - Total Heavy Metals | ≤10 ppm | Conforms | ICP-MS |
| - Arsenic (As) | ≤1.0 ppm | Conforms | GB 5009.11-2014 |
| - Lead (Pb) | ≤1.0 ppm | Conforms | GB 5009.12-2017 |
| - Mercury (Hg) | ≤0.5 ppm | Conforms | GB 5009.17-2014 |
| - Cadmium (Cd) | ≤1.0 ppm | Conforms | GB 5009.15-2014 |
| Microbiological Tests | |||
| - Total Plate Count | ≤1,000 cfu/g | Conforms | CP2015 |
| - Yeast & Mold | ≤100 cfu/g | Conforms | CP2015 |
| - E. coli | Negative | Conforms | CP2015 |
| - Salmonella | Negative | Conforms | CP2015 |
| - Staphylococcus | Negative | Conforms | CP2015 |
Compliance & Certifications:
- GMP (Good Manufacturing Practice) Certified
- ISO 9001:2015 Quality Management System
- HACCP & FSSC 22000 Food Safety Standards
- Halal & Kosher Certified (Available upon request)
- Non-GMO, Gluten-Free, Allergen-Free
Scientifically Supported Benefits of Dihydromyricetin Extract
1. Accelerates Alcohol Metabolism & Reduces Intoxication
Dihydromyricetin has been extensively studied for its alcohol-degrading properties. Research indicates that DHM:
- Enhances the activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), the enzymes responsible for breaking down ethanol into non-toxic byproducts.
- Shortens the duration of alcohol-induced sedation (Loss of Righting Reflex, LORR) in animal studies, suggesting a faster recovery from intoxication.
- Reduces blood alcohol concentration (BAC) levels more rapidly than placebo, with some studies showing recovery in as little as 5 minutes compared to 70 minutes in control groups.
2. Protects Liver Function & Prevents Alcohol-Induced Damage
Chronic alcohol consumption can lead to oxidative stress, fatty liver disease, and inflammation. Dihydromyricetin extract helps by:
- Neutralizing free radicals and reducing lipid peroxidation, protecting hepatocytes from oxidative damage.
- Modulating lipid metabolism, preventing alcohol-induced fatty liver (steatosis).
- Supporting liver detoxification pathways, aiding in the clearance of acetaldehyde, a toxic byproduct of ethanol metabolism.
3. Reduces Alcohol Cravings & Withdrawal Symptoms
Preclinical studies suggest that dihydromyricetin extract may help:
- Decrease alcohol consumption in animal models by modulating GABA receptors, which are linked to addiction and reward pathways.
- Alleviate withdrawal symptoms, including anxiety and restlessness, by stabilizing neurotransmitter activity.
- Support long-term sobriety by reducing the reinforcing effects of alcohol.
4. Neuroprotective & Anti-Inflammatory Effects
Beyond alcohol-related benefits, dihydromyricetin exhibits:
- Anti-inflammatory properties, reducing NF-κB and COX-2 expression, which are markers of inflammation.
- Neuroprotective effects, potentially aiding in cognitive function and neurodegenerative disease prevention.
- Antioxidant activity, comparable to vitamin C and E, helping combat oxidative stress in various tissues.
Industry Applications of Dihydromyricetin Extract
Our high-purity dihydromyricetin powder is a versatile ingredient with applications across multiple industries:
1. Nutraceuticals & Dietary Supplements
- Hangover relief capsules & tablets – Helps speed up alcohol metabolism and reduce next-day symptoms.
- Liver detox & support formulas – Combined with milk thistle, NAC, and silymarin for enhanced hepatoprotection.
- Anti-addiction supplements – Used in alcohol cessation aids to reduce cravings and withdrawal effects.
2. Functional Foods & Beverages
- Alcohol-neutralizing drinks – Added to energy drinks, shots, and recovery beverages to mitigate intoxication.
- Healthy alcoholic beverages – Incorporated into low-alcohol or functional beers and cocktails to enhance safety.
- Fortified foods – Used in snacks, protein bars, and health tonics for liver support.
3. Pharmaceutical & Cosmeceutical Formulations
- Drug development – Investigated for alcohol use disorder (AUD) treatments and liver-protective medications.
- Topical antioxidants – Used in skincare products for its anti-aging and free radical-scavenging properties.
4. Animal Nutrition & Feed Additives
- Livestock & poultry supplements – Supports liver health in farm animals exposed to mycotoxins or metabolic stress.
- Pet nutrition – Added to dog and cat supplements for detoxification and liver function support.
Product Features & Competitive Advantages
✅ High Purity (98% Min.) – Ensures maximum efficacy in formulations.
✅ Superior Bioavailability – Optimized for rapid absorption and utilization.
✅ Stable & Soluble – Water-soluble (with slight ethanol solubility), making it easy to incorporate into liquids, capsules, and powders.
✅ Non-GMO & Allergen-Free – Safe for vegan, gluten-free, and hypoallergenic products.
✅ Long Shelf Life – 24 months when stored in cool, dry conditions (below 25°C, sealed in original packaging).
✅ Customizable Packaging – Available in 1kg, 5kg, 10kg, and 25kg sealed aluminum foil bags or fiber drums.
Storage & Handling Recommendations
To preserve potency and stability, we recommend:
- Store in a tightly sealed container away from light, heat, and moisture.
- Avoid exposure to strong odors to prevent contamination.
- Use within 24 months from the date of manufacture for optimal freshness.
Why Choose Botanical Essence as Your Dihydromyricetin Supplier?
As a leading manufacturer and exporter of plant extracts, Botanical Essence offers:
✔ Premium Quality Assurance – Every batch is third-party tested for purity, heavy metals, and microbiological safety.
✔ Consistent Supply Chain – Reliable sourcing from sustainable Hovenia dulcis plantations with traceable origins.
✔ Technical & Formulation Support – Our R&D team provides custom blending, private labeling, and formulation guidance.
✔ Competitive Pricing & Bulk Discounts – Wholesale and OEM/ODM options available for large-scale buyers.
✔ Global Shipping & Logistics – Fast delivery with DHL, FedEx, and sea freight options to North America, Europe, and Asia.
✔ Regulatory Compliance – FDA-registered facility, REACH-compliant, and export-ready documentation (COA, MSDS, TDS).
How to Buy Dihydromyricetin Extract in Bulk?
For wholesale inquiries, bulk orders, or custom formulations, contact our dedicated sales team today:
📧 Email: [email protected]
🌍 Website: [Botanical Essence – Your Trusted Plant Extract Supplier]
Whether you are a nutraceutical manufacturer, functional food producer, or pharmaceutical company, our high-quality dihydromyricetin extract is the perfect choice for your next liver-support, alcohol-metabolism, or detoxification product.
Request a quote, sample, or technical data sheet now!
