Product Overview: Citrus Bioflavonoids Hesperidin
Citrus Bioflavonoids Hesperidin is a naturally occurring flavonoid glycoside predominantly extracted from the peels of citrus fruits, including oranges, lemons, grapefruits, and tangerines. As a key member of the bioflavonoid family, hesperidin works synergistically with vitamin C to enhance its absorption, support collagen synthesis, and strengthen capillary integrity.
This high-purity hesperidin extract is widely recognized in the nutraceutical, pharmaceutical, and cosmetic industries for its antioxidant, anti-inflammatory, and vascular-protective properties. Available in powder or crystalline form, it is a versatile ingredient for dietary supplements, functional foods, skincare formulations, and pharmaceutical applications.
Scientific & Botanical Background
Source & Extraction
- Botanical Origin: Citrus aurantium (Bitter Orange), Citrus sinensis (Sweet Orange), and other Citrus species.
- Plant Part Used: Dried citrus peels (flavedo and albedo layers).
- Extraction Method: Solvent extraction (water & ethanol) followed by purification and crystallization to ensure high bioactivity and stability.
- Active Compound: Hesperidin (C₂₈H₃₄O₁₅), a flavanone glycoside with potent free radical scavenging and vascular-supporting properties.
Chemical & Physical Properties
| Parameter | Specification |
|---|---|
| Appearance | Orange-yellow to yellow fine powder |
| Assay (Dry Basis) | 98.0% – 102.0% (UV) |
| Solubility | Freely soluble in water (enhanced bioavailability) |
| pH Value | 4.5 – 6.5 |
| Loss on Drying | ≤ 5% (GB 5009.3) |
| Sulphated Ash | ≤ 0.5% (GB 5009.4) |
| Heavy Metals | As ≤ 1.0 ppm, Pb ≤ 2.0 ppm, Hg ≤ 1.0 ppm |
| Microbiological | Total Plate Count ≤ 10,000 cfu/g, Yeast & Mold ≤ 100 cfu/g, E. coli & Staphylococcus Negative |
Key Benefits & Applications of Citrus Bioflavonoids Hesperidin
1. Nutraceutical & Dietary Supplement Applications
Hesperidin is a bioactive compound with multiple health benefits, making it a high-demand ingredient for:
- Cardiovascular Support: Enhances blood circulation, reduces capillary fragility, and supports venous health.
- Antioxidant & Anti-Inflammatory Effects: Neutralizes free radicals, reducing oxidative stress and inflammation.
- Immune Modulation: Works synergistically with vitamin C to boost immune function and collagen production.
- Metabolic Health: May aid in glucose metabolism and lipid regulation, supporting metabolic wellness.
- Joint & Connective Tissue Health: Promotes collagen integrity, benefiting joint mobility and skin elasticity.
Common Dosage Forms:
- Capsules & Tablets (500 mg – 1,000 mg per serving)
- Powder Blends (for functional beverages & nutritional powders)
- Softgels & Chewables (for enhanced bioavailability)
2. Cosmetic & Skincare Applications
Hesperidin’s dermatological benefits make it a valuable active ingredient in:
- Anti-Aging Formulations: Reduces oxidative damage, improving skin firmness and radiance.
- Brightening & Even-Tone Products: Inhibits melanin production, helping to fade dark spots and hyperpigmentation.
- Soothing & Barrier-Repair Creams: Strengthens the skin moisture barrier, reducing dryness and irritation.
- Sun Protection Enhancers: Works alongside SPF ingredients to neutralize UV-induced free radicals.
Formulation Compatibility:
- Water-based serums & lotions
- Emulsions & creams
- Masks & leave-on treatments
3. Pharmaceutical & Functional Food Applications
- Vascular Health Supplements: Used in venotonic formulations to support circulatory function.
- Functional Beverages: Added to juices, teas, and energy drinks for antioxidant enrichment.
- Sports Nutrition: Included in recovery supplements for anti-inflammatory support.
Why Choose Botanical Essence’s Citrus Bioflavonoids Hesperidin?
1. Superior Quality & Purity
- High-Purity Extraction: Minimum 98% hesperidin content (UV-tested).
- Strict Quality Control: Compliant with GB, USP, and EP standards.
- Heavy Metal & Microbial Testing: Ensures safety and regulatory compliance for global markets.
2. Sustainable & Traceable Sourcing
- Ethically Sourced Citrus Peels: From GMP-certified suppliers with non-GMO, pesticide-free raw materials.
- Eco-Friendly Extraction: Uses food-grade solvents (water & ethanol) with low environmental impact.
3. Customizable & Scalable Supply
- Flexible Packaging: Available in 1 kg, 5 kg, 10 kg, and 25 kg sealed drums or bags.
- Private Label & Bulk Options: Tailored solutions for manufacturers, contract formulators, and private-label brands.
- Stable Shelf Life: 24 months when stored in a cool, dry place (below 25°C, away from direct sunlight).
4. Regulatory & Certification Support
- ISO 9001 & HACCP Certified manufacturing.
- Halal & Kosher compliant (available upon request).
- Third-Party Testing: COA (Certificate of Analysis) provided for every batch.
Technical & Formulation Considerations
Solubility & Stability
- Water-Soluble: Easily dispersible in aqueous solutions, making it ideal for beverages, syrups, and liquid supplements.
- pH Stability: Remains stable in pH 4.5–6.5, compatible with most nutraceutical and cosmetic formulations.
- Heat & Light Sensitivity: Store in airtight, opaque containers to prevent degradation.
Synergistic Ingredients
Hesperidin works well with:
- Vitamin C (enhances absorption & antioxidant effects)
- Quercetin & Rutin (boosts vascular & immune support)
- Collagen Peptides (supports skin & joint health)
- Hyaluronic Acid (enhances moisture retention in skincare)
Recommended Usage Levels
| Application | Typical Dosage |
|---|---|
| Dietary Supplements | 500 mg – 1,000 mg/day |
| Functional Foods | 100 mg – 500 mg/serving |
| Skincare Formulations | 0.5% – 2% (in creams/serums) |
Where to Buy Premium Citrus Bioflavonoids Hesperidin?
Botanical Essence is a leading supplier of high-quality hesperidin extract, specializing in plant-based ingredients for the nutraceutical, cosmetic, and pharmaceutical industries.
Why Partner With Us?
✅ GMP-Standard Manufacturing – Strict quality control from raw material to final product.
✅ Competitive Pricing – Bulk discounts for wholesale, OEM, and private-label clients.
✅ Fast & Reliable Shipping – Global logistics with DHL, FedEx, and sea freight options.
✅ Technical & Formulation Support – Expert guidance for product development and regulatory compliance.
✅ Free Samples Available – Request a sample for testing before bulk orders.
Contact Us for Quotations & Bulk Inquiries:
📧 Email: [email protected]
🌍 Global Supply Chain: Serving North America, Europe, Asia, and beyond
Frequently Asked Questions (FAQs)
Q: Is Citrus Bioflavonoids Hesperidin safe for long-term use?
A: Yes, hesperidin is generally recognized as safe (GRAS) when consumed within recommended dosages. It has been extensively studied for safety and efficacy in human nutrition.
Q: Can hesperidin be used in vegan or vegetarian products?
A: Absolutely. Our hesperidin extract is 100% plant-derived, making it suitable for vegan, vegetarian, and halal/kosher formulations.
Q: What is the difference between hesperidin and hesperidin methyl chalcone?
A: Hesperidin methyl chalcone (HMC) is a modified, more bioavailable form of hesperidin, offering enhanced absorption in supplements. Our standard hesperidin extract is the natural glycoside form, ideal for general applications.
Q: Do you provide third-party testing certificates?
A: Yes, every batch comes with a detailed COA, including HPLC/UV testing, heavy metal analysis, and microbial reports.
Q: What is the minimum order quantity (MOQ)?
A: Our MOQ starts at 1 kg, with flexible bulk pricing for larger orders. Contact us for custom packaging and private-label options.
Botanical Essence – Your Trusted Partner for Premium Plant Extracts & Nutraceutical Ingredients.




